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Synthesis and Biological Evaluation of New Quinoxaline Derivatives of ICF01012 as Melanoma-Targeting Probes

[Image: see text] The aim of this study was the synthesis and pharmacokinetic selection of a best melanin-targeting ligand for addressing anticancer agents to pigmented melanoma. Seven quinoxaline carboxamide derivatives were synthesized and radiolabeled with iodine-125. Biodistribution studies of c...

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Detalhes bibliográficos
Main Authors: El Aissi, Radhia, Liu, Jianrong, Besse, Sophie, Canitrot, Damien, Chavignon, Olivier, Chezal, Jean-Michel, Miot-Noirault, Elisabeth, Moreau, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027609/
https://ncbi.nlm.nih.gov/pubmed/24900863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400468x
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