CFTR Modulator Therapy with Lumacaftor/Ivacaftor Alters Plasma Concentrations of Lipid-Soluble Vitamins A and E in Patients with Cystic Fibrosis

Rationale: Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leads to impaired pancreatic function and therefore reduced intestinal absorption of lipids and fat-soluble vitamins especially in patients with CF developing pancreatic insuf...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Sommerburg, Olaf, Hämmerling, Susanne, Schneider, S. Philipp, Okun, Jürgen, Langhans, Claus-Dieter, Leutz-Schmidt, Patricia, Wielpütz, Mark O., Siems, Werner, Gräber, Simon Y., Mall, Marcus A., Stahl, Mirjam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003491/
https://ncbi.nlm.nih.gov/pubmed/33808590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10030483
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