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Synthesis, Antifungal Activity, and 3D-QSAR Study of Novel Nopol-Derived 1,3,4-Thiadiazole-Thiourea Compounds

A series of novel nopol derivatives bearing the 1,3,4-thiadiazole-thiourea moiety were designed and synthesized by multi-step reactions in search of potent natural product-based antifungal agents. Their structures were confirmed by FT-IR, NMR, ESI-MS, and elemental analysis. Antifungal activity of t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Ming, Duan, Wen-Gui, Lin, Gui-Shan, Fan, Zhong-Tian, Wang, Xiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003325/
https://ncbi.nlm.nih.gov/pubmed/33803890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26061708
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