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Recent Updates on the Significance of KRAS Mutations in Colorectal Cancer Biology

The most commonly mutated isoform of RAS among all cancer subtypes is KRAS. In this review, we focus on the special role of KRAS mutations in colorectal cancer (CRC), aiming to collect recent data on KRAS-driven enhanced cell signalling, in vitro and in vivo research models, and CRC development-rela...

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發表在:Cells
Main Authors: László, Loretta, Kurilla, Anita, Takács, Tamás, Kudlik, Gyöngyi, Koprivanacz, Kitti, Buday, László, Vas, Virag
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002639/
https://ncbi.nlm.nih.gov/pubmed/33802849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030667
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