Significance of the Tks4 scaffold protein in bone tissue homeostasis

The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow mesenchymal stem/stromal cells (BM-MSCs). Tks4 (encoded by the Sh3pxd2b gene...

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Publicado no:Sci Rep
Main Authors: Vas, Virag, Kovács, Tamás, Körmendi, Szandra, Bródy, Andrea, Kudlik, Gyöngyi, Szeder, Bálint, Mező, Diána, Kállai, Dóra, Koprivanacz, Kitti, Merő, Balázs L., Dülk, Metta, Tóvári, József, Vajdovich, Péter, Şenel, Ş. Neslihan, Özcan, Ilknur, Helyes, Zsuzsanna, Dobó-Nagy, Csaba, Buday, László
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453952/
https://ncbi.nlm.nih.gov/pubmed/30962481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42250-6
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