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Autocrine TGFβ1 Opposes Exogenous TGFβ1-Induced Cell Migration and Growth Arrest through Sustainment of a Feed-Forward Loop Involving MEK-ERK Signaling

SIMPLE SUMMARY: Transforming growth factor (TGF) β signaling is intimately involved in nearly all aspects of tumor development and is known for its role as both a tumor suppressor in benign tissues and a tumor promoter in advanced cancers. This dual role is also reflected by cancer cell-produced TGF...

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Bibliografiset tiedot
Julkaisussa:Cancers (Basel)
Päätekijät: Ungefroren, Hendrik, Christl, Jessica, Eiden, Caroline, Wellner, Ulrich F., Lehnert, Hendrik, Marquardt, Jens-Uwe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002526/
https://ncbi.nlm.nih.gov/pubmed/33802809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061357
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