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IRE1α Is a Therapeutic Target for Cystic Fibrosis Airway Inflammation
New anti-inflammatory treatments are needed for CF airway disease. Studies have implicated the endoplasmic reticulum stress transducer inositol requiring enzyme 1α (IRE1α) in CF airway inflammation. The activation of IRE1α promotes activation of its cytoplasmic kinase and RNase, resulting in mRNA sp...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8002512/ https://ncbi.nlm.nih.gov/pubmed/33802742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063063 |
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