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Modulation of Tubular pH by Acetazolamide in a Ca(2+) Transport Deficient Mice Facilitates Calcium Nephrolithiasis
Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca(2+) supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While such CaP crystals are known to act as a nidus for CaP/calcium oxalate (CaOx) mixed stone formation, the regulation of...
Enregistré dans:
| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8002449/ https://ncbi.nlm.nih.gov/pubmed/33802660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063050 |
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