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Abrogation of store-operated Ca(2+) entry protects against crystal-induced ER stress in human proximal tubular cells
Calcium crystal internalization into proximal tubular (PT) cells results in acute kidney injury, nephrocalcinosis, chronic kidney disease (CKD), and kidney-stone formation. Ca(2+) supersaturation in PT luminal fluid induces calcium crystal formation, leading to aberrant crystal internalization into...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680047/ https://ncbi.nlm.nih.gov/pubmed/31396401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0203-5 |
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