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Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F(0)F(1)-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy
Down syndrome (DS) is a major genetic cause of intellectual disability. DS pathogenesis has not been fully elucidated, and no specific pharmacological therapy is available. DYRK1A overexpression, oxidative stress and mitochondrial dysfunction were described in trisomy 21. Epigallocatechin-3-gallate...
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| Publicado no: | Antioxidants (Basel) |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8002266/ https://ncbi.nlm.nih.gov/pubmed/33809669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10030469 |
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