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Structural Polymorphism of Sorafenib Tosylate as a Key Factor in Its Solubility Differentiation

The presence of active pharmaceutical ingredients (APIs) in the forms of different polymorphic states can induce differences in their physicochemical properties. In the case of poorly soluble APIs, like the oncological drug sorafenib tosylate, small variations in solubility may result in large bioav...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Wiergowska, Gabriela, Stasiłowicz, Anna, Miklaszewski, Andrzej, Lewandowska, Kornelia, Cielecka-Piontek, Judyta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002161/
https://ncbi.nlm.nih.gov/pubmed/33805754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030384
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