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Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells

5-Fluorouracil (5-FU) is a cornerstone drug used in the treatment of colorectal cancer (CRC). However, the development of resistance to 5-FU and its analogs remain an unsolved problem in CRC treatment. In this study, we investigated the molecular mechanisms and tumor biological aspects of 5-FU resis...

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Pubblicato in:Int J Mol Sci
Autori principali: Kurasaka, Chinatsu, Ogino, Yoko, Sato, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002131/
https://ncbi.nlm.nih.gov/pubmed/33805673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062916
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