Moscatilin Inhibits Metastatic Behavior of Human Hepatocellular Carcinoma Cells: A Crucial Role of uPA Suppression via Akt/NF-κB-Dependent Pathway

Hepatocellular carcinoma (HCC) frequently shows early invasion into blood vessels as well as intrahepatic metastasis. Innovations of novel small-molecule agents to block HCC invasion and subsequent metastasis are urgently needed. Moscatilin is a bibenzyl derivative extracted from the stems of a trad...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Yu, Chen-Lin, Weng, Meng-Shih, Chen, Wei-Cheng, Chien, Kai-Ting, Chi, Chih-Wen, Chung, Ching-Hu, Huang, Chia-Wen, Wang, Po-Chuan, Chen, Chien-Chih, Tsai, An-Chi, Liu, Shih-Chia, Wang, Shih-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002083/
https://ncbi.nlm.nih.gov/pubmed/33805784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062930
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