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A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4)

Monocarboxylate transporters (MCTs) are of great research interest for their role in cancer cell metabolism and their potential ability to transport pharmacologically relevant compounds across the membrane. Each member of the MCT family could potentially provide novel therapeutic approaches to vario...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Papakonstantinou, Eleni, Vlachakis, Dimitrios, Thireou, Trias, Vlachoyiannopoulos, Panayiotis G., Eliopoulos, Elias
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001682/
https://ncbi.nlm.nih.gov/pubmed/33805725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062918
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