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Pan-Cancer Analysis of Human Kinome Gene Expression and Promoter DNA Methylation Identifies Dark Kinase Biomarkers in Multiple Cancers

SIMPLE SUMMARY: Due to their central role in many biological processes, studies on protein kinases are an area of active research. In the last few decades, several inhibitors that target kinases have been approved by U.S. Food and Drug Administration (FDA). However, a large proportion of kinases rem...

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Foilsithe in:Cancers (Basel)
Main Authors: Southekal, Siddesh, Mishra, Nitish Kumar, Guda, Chittibabu
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001681/
https://ncbi.nlm.nih.gov/pubmed/33801837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061189
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