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Pan-Cancer Analysis of Human Kinome Gene Expression and Promoter DNA Methylation Identifies Dark Kinase Biomarkers in Multiple Cancers

SIMPLE SUMMARY: Due to their central role in many biological processes, studies on protein kinases are an area of active research. In the last few decades, several inhibitors that target kinases have been approved by U.S. Food and Drug Administration (FDA). However, a large proportion of kinases rem...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Southekal, Siddesh, Mishra, Nitish Kumar, Guda, Chittibabu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001681/
https://ncbi.nlm.nih.gov/pubmed/33801837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061189
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