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iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives

Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect cardiac ion channels or their accessory proteins. The main hurdle for the study of the functional effects of those va...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Nijak, Aleksandra, Saenen, Johan, Labro, Alain J., Schepers, Dorien, Loeys, Bart L., Alaerts, Maaike
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001521/
https://ncbi.nlm.nih.gov/pubmed/33802229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062825
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