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iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives

Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect cardiac ion channels or their accessory proteins. The main hurdle for the study of the functional effects of those va...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nijak, Aleksandra, Saenen, Johan, Labro, Alain J., Schepers, Dorien, Loeys, Bart L., Alaerts, Maaike
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001521/
https://ncbi.nlm.nih.gov/pubmed/33802229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062825
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