Nef Obtained from Individuals with HIV-1 Vary in Their Ability to Antagonize SERINC3- and SERINC5-Mediated HIV-1 Restriction

Nef is a multifunctional viral protein that has the ability to downregulate cell surface molecules, including CD4 and major histocompatibility complex class I (MHC-I) and, as recently shown, also members of the serine incorporator family (SERINC). Here, we analyzed the impact of naturally occurring...

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Udgivet i:Viruses
Main Authors: Kruize, Zita, van Nuenen, Ad C., van Wijk, Stan W., Girigorie, Arginell F., van Dort, Karel A., Booiman, Thijs, Kootstra, Neeltje A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000780/
https://ncbi.nlm.nih.gov/pubmed/33800773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13030423
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