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Structural and Functional Characterization of the ABCC6 Transporter in Hepatic Cells: Role on PXE, Cancer Therapy and Drug Resistance

Pseudoxanthoma elasticum (PXE) is a complex autosomal recessive disease caused by mutations of ABCC6 transporter and characterized by ectopic mineralization of soft connective tissues. Compared to the other ABC transporters, very few studies are available to explain the structural components and wor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bisaccia, Faustino, Koshal, Prashant, Abruzzese, Vittorio, Castiglione Morelli, Maria Antonietta, Ostuni, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000515/
https://ncbi.nlm.nih.gov/pubmed/33799762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062858
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