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Electrochromic shift supports the membrane destabilization model of Tat-mediated transport and shows ion leakage during Sec transport

The mechanism and pore architecture of the Tat complex during transport of folded substrates remain a mystery, partly due to rapid dissociation after translocation. In contrast, the proteinaceous SecY pore is a persistent structure that needs only to undergo conformational shifts between “closed” an...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Asher, Anthony H., Theg, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000419/
https://ncbi.nlm.nih.gov/pubmed/33723047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018122118
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