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Sec- and Tat-Dependent Translocation of β-Lactamases across the Escherichia coli Inner Membrane

β-Lactamases represent the major resistance mechanism of gram-negative bacteria against β-lactam antibiotics. The amino acid sequences of these proteins vary widely, but all are located in the periplasm of bacteria. In this study, we investigated the translocation mechanism of representative β-lacta...

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Detalhes bibliográficos
Main Authors: Pradel, N., Delmas, J., Wu, L. F., Santini, C. L., Bonnet, R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612164/
https://ncbi.nlm.nih.gov/pubmed/18981261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00642-08
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