A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6

Ykt6 is a soluble N-ethylmaleimide sensitive factor activating protein receptor (SNARE) critically involved in diverse vesicular fusion pathways. While most SNAREs rely on transmembrane domains for their activity, Ykt6 dynamically cycles between the cytosol and membrane-bound compartments where it i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: McGrath, Kaitlyn, Agarwal, Shivani, Tonelli, Marco, Dergai, Mykola, Gaeta, Anthony L., Shum, Andrew K., Lacoste, Jessica, Zhang, Yongbo, Wen, Wenyu, Chung, Daayun, Wiersum, Grant, Shevade, Aishwarya, Zaichick, Sofia, van Rossum, Damian B., Shuvalova, Ludmilla, Savas, Jeffrey N., Kuchin, Sergei, Taipale, Mikko, Caldwell, Kim A., Caldwell, Guy A., Fasshauer, Dirk, Caraveo, Gabriela
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2021
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000380/
https://ncbi.nlm.nih.gov/pubmed/33723042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016730118
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