A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6

Ykt6 is a soluble N-ethylmaleimide sensitive factor activating protein receptor (SNARE) critically involved in diverse vesicular fusion pathways. While most SNAREs rely on transmembrane domains for their activity, Ykt6 dynamically cycles between the cytosol and membrane-bound compartments where it i...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: McGrath, Kaitlyn, Agarwal, Shivani, Tonelli, Marco, Dergai, Mykola, Gaeta, Anthony L., Shum, Andrew K., Lacoste, Jessica, Zhang, Yongbo, Wen, Wenyu, Chung, Daayun, Wiersum, Grant, Shevade, Aishwarya, Zaichick, Sofia, van Rossum, Damian B., Shuvalova, Ludmilla, Savas, Jeffrey N., Kuchin, Sergei, Taipale, Mikko, Caldwell, Kim A., Caldwell, Guy A., Fasshauer, Dirk, Caraveo, Gabriela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000380/
https://ncbi.nlm.nih.gov/pubmed/33723042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016730118
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