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Oocyte age and preconceptual alcohol use are highly correlated with epigenetic imprinting of a noncoding RNA (nc886)

Genomic imprinting occurs before fertilization, impacts every cell of the developing child, and may be sensitive to environmental perturbations. The noncoding RNA, nc886 (also called VTRNA2-1) is the only known example of the ∼100 human genes imprinted by DNA methylation, that shows polymorphic impr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Carpenter, Brittany L., Remba, Tanaka K., Thomas, Stacey L., Madaj, Zachary, Brink, Lucy, Tiedemann, Rochelle L., Odendaal, Hein J., Jones, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000112/
https://ncbi.nlm.nih.gov/pubmed/33723081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026580118
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