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The Uncovered Function of the Drosophila GBA1a-Encoded Protein

Human GBA1 encodes lysosomal acid β-glucocerebrosidase (GCase), which hydrolyzes cleavage of the beta-glucosidic linkage of glucosylceramide (GlcCer). Mutations in this gene lead to reduced GCase activity, accumulation of glucosylceramide and glucosylsphingosine, and development of Gaucher disease (...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Cabasso, Or, Paul, Sumit, Maor, Gali, Pasmanik-Chor, Metsada, Kallemeijn, Wouter, Aerts, Johannes, Horowitz, Mia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000066/
https://ncbi.nlm.nih.gov/pubmed/33809074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030630
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