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Resurrecting the Mysteries of Big Tau
Tau, a microtubule-associated protein that modifies the dynamic properties and organization of microtubules in neurons and affects axonal transport, shows remarkable heterogeneity, with multiple isoforms (45–65 kDa) generated by alternative splicing. A high-molecular-weight (HMW) isoform (110 kDa) t...
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| Publicado en: | Trends Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7999525/ https://ncbi.nlm.nih.gov/pubmed/32434664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2020.04.007 |
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