Comprehensive Genomic Characterization of Fifteen Early-Onset Lynch-Like Syndrome Colorectal Cancers

SIMPLE SUMMARY: The most prevalent type of hereditary colorectal cancer is called Lynch syndrome and it is characterized by a tumor phenotype called microsatellite instability (MSI). This disease is a consequence of germline (inheritable) variants in any of the four mismatch repair (MMR) DNA genes,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Golubicki, Mariano, Díaz-Gay, Marcos, Bonjoch, Laia, Franch-Expósito, Sebastià, Muñoz, Jenifer, Cuatrecasas, Miriam, Ocaña, Teresa, Iseas, Soledad, Mendez, Guillermo, Carballido, Marcela, Robbio, Juan, Cisterna, Daniel, Roca, Enrique, Castells, Antoni, Balaguer, Francesc, Castellví-Bel, Sergi, Antelo, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999079/
https://ncbi.nlm.nih.gov/pubmed/33809179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061259
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