Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation

Evidence indicates that dysfunctional heterogeneous ribonucleoprotein A1 (hnRNPA1; A1) contributes to the pathogenesis of neurodegeneration in multiple sclerosis. Understanding molecular mechanisms of neurodegeneration in multiple sclerosis may result in novel therapies that attenuate neurodegenerat...

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Publicado en:Int J Mol Sci
Autores principales: Clarke, Joseph-Patrick W. E., Thibault, Patricia A., Salapa, Hannah E., Kim, David E., Hutchinson, Catherine, Levin, Michael C.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998649/
https://ncbi.nlm.nih.gov/pubmed/33809384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062909
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