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DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients

SIMPLE SUMMARY: Functional aneuploidy as determined by expression of the 70 genes of the CIN70 score, influences prognosis. The importance of DNA repair protein expression and activity in this context is unclear. We can show here that a high CIN70 score is associated with increased expression of 44...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bold, Ioan T., Specht, Ann-Kathrin, Droste, Conrad F., Zielinski, Alexandra, Meyer, Felix, Clauditz, Till S., Münscher, Adrian, Werner, Stefan, Rothkamm, Kai, Petersen, Cordula, Borgmann, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998578/
https://ncbi.nlm.nih.gov/pubmed/33801877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061194
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