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The Genetic and Clinical Features of FOXL2-Related Blepharophimosis, Ptosis and Epicanthus Inversus Syndrome

Blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) is a craniofacial disorder caused by heterozygous variants of the forkhead box L2 (FOXL2) gene. It shows autosomal dominant inheritance but can also occur sporadically. Depending on the mutation, two phenotypic subtypes have been desc...

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Foilsithe in:Genes (Basel)
Main Authors: Méjécase, Cécile, Nigam, Chandni, Moosajee, Mariya, Bladen, John C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998575/
https://ncbi.nlm.nih.gov/pubmed/33806295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12030364
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