Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53

The tumor suppressor p53 is inactivated by mutation in approximately 50% of human cancers. Small molecules that bind and stabilize those mutants may represent effective anticancer drugs. Herein, we report the tumor cell growth inhibitory activity of carbazole alkaloids and amino derivatives, as well...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Long, Solida, Loureiro, Joana B., Carvalho, Carla, Gales, Luís, Saraiva, Lucília, Pinto, Madalena M. M., Puthongking, Ploenthip, Sousa, Emília
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998292/
https://ncbi.nlm.nih.gov/pubmed/33804175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26061637
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki