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Marine Natural Products as Models to Circumvent Multidrug Resistance

Multidrug resistance (MDR) to anticancer drugs is a serious health problem that in many cases leads to cancer treatment failure. The ATP binding cassette (ABC) transporter P-glycoprotein (P-gp), which leads to premature efflux of drugs from cancer cells, is often responsible for MDR. On the other ha...

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Vydáno v:Molecules
Hlavní autoři: Long, Solida, Sousa, Emília, Kijjoa, Anake, Pinto, Madalena M. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273648/
https://ncbi.nlm.nih.gov/pubmed/27399665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21070892
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