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Coupling Mass Spectral and Genomic Information to Improve Bacterial Natural Product Discovery Workflows

Bacterial natural products possess potent bioactivities and high structural diversity and are typically encoded in biosynthetic gene clusters. Traditional natural product discovery approaches rely on UV- and bioassay-guided fractionation and are limited in terms of dereplication. Recent advances in...

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Bibliografski detalji
Izdano u:Mar Drugs
Glavni autor: Crüsemann, Max
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998270/
https://ncbi.nlm.nih.gov/pubmed/33807702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19030142
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