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Coupling Mass Spectral and Genomic Information to Improve Bacterial Natural Product Discovery Workflows

Bacterial natural products possess potent bioactivities and high structural diversity and are typically encoded in biosynthetic gene clusters. Traditional natural product discovery approaches rely on UV- and bioassay-guided fractionation and are limited in terms of dereplication. Recent advances in...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Autor principal: Crüsemann, Max
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998270/
https://ncbi.nlm.nih.gov/pubmed/33807702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19030142
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