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A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons
The RNA-binding protein SFPQ plays an important role in neuronal development and has been associated with several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s disease. Here, we report that loss of sfpq leads to premature t...
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| Foilsithe in: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7997972/ https://ncbi.nlm.nih.gov/pubmed/33771997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22098-z |
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