Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy

BACKGROUND: IgA nephropathy is thought to be an autoimmune disease wherein galactose-deficient IgA1 (Gd-IgA1) is recognized by IgG autoantibodies, resulting in formation and renal accumulation of nephritogenic immune complexes. Although this hypothesis is supported by recent findings that, in renal...

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Publicado no:J Autoimmun
Principais autores: Moldoveanu, Zina, Suzuki, Hitoshi, Reily, Colin, Satake, Kenji, Novak, Lea, Xu, Nuo, Huang, Zhi-Qiang, Knoppova, Barbora, Khan, Atlas, Hall, Stacy, Yanagawa, Hiroyuki, Brown, Rhubell, Winstead, Colleen J., O’Quinn, Darrell B., Weinmann, Amy, Gharavi, Ali G., Kiryluk, Krzysztof, Julian, Bruce A., Weaver, Casey T., Suzuki, Yusuke, Novak, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997636/
https://ncbi.nlm.nih.gov/pubmed/33508637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2021.102593
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