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Targeted design of drug binding sites in the main protease of SARS-CoV-2 reveals potential signatures of adaptation
Several existing drugs are currently being tested worldwide to treat COVID-19 patients. Recent data indicate that SARS-CoV-2 is rapidly evolving into more transmissible variants. It is therefore highly possible that SARS-CoV-2 can accumulate adaptive mutations modulating drug susceptibility and hamp...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7997393/ https://ncbi.nlm.nih.gov/pubmed/33813274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.03.118 |
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