Innovative IgG Biomarkers Based on Phage Display Microbial Amyloid Mimotope for State and Stage Diagnosis in Alzheimer’s Disease

[Image: see text] An innovative approach to identify new conformational antigens of Aβ(1–42) recognized by IgG autoantibodies as biomarkers of state and stage in Alzheimer’s disease (AD) patients is described. In particular, through the use of bioinformatics modeling, conformational similarities bet...

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Bibliografiske detaljer
Udgivet i:ACS Chem Neurosci
Main Authors: De Plano, Laura M., Carnazza, Santina, Franco, Domenico, Rizzo, Maria Giovanna, Conoci, Sabrina, Petralia, Salvatore, Nicoletti, Alessandra, Zappia, Mario, Campolo, Michela, Esposito, Emanuela, Cuzzocrea, Salvatore, Guglielmino, Salvatore P. P.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997372/
https://ncbi.nlm.nih.gov/pubmed/32176482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00549
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