Innovative IgG Biomarkers Based on Phage Display Microbial Amyloid Mimotope for State and Stage Diagnosis in Alzheimer’s Disease

[Image: see text] An innovative approach to identify new conformational antigens of Aβ(1–42) recognized by IgG autoantibodies as biomarkers of state and stage in Alzheimer’s disease (AD) patients is described. In particular, through the use of bioinformatics modeling, conformational similarities bet...

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Pubblicato in:ACS Chem Neurosci
Autori principali: De Plano, Laura M., Carnazza, Santina, Franco, Domenico, Rizzo, Maria Giovanna, Conoci, Sabrina, Petralia, Salvatore, Nicoletti, Alessandra, Zappia, Mario, Campolo, Michela, Esposito, Emanuela, Cuzzocrea, Salvatore, Guglielmino, Salvatore P. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997372/
https://ncbi.nlm.nih.gov/pubmed/32176482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00549
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