Mycobacterium leprae promotes triacylglycerol de novo synthesis through induction of GPAT3 expression in human premonocytic THP-1 cells

Mycobacterium leprae (M. leprae) is the etiological agent of leprosy, and the skin lesions of lepromatous leprosy are filled with numerous foamy or xanthomatous histiocytes that are parasitized by M. leprae. Lipids are an important nutrient for the intracellular survival of M. leprae. In this study,...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Tanigawa, Kazunari, Hayashi, Yasuhiro, Hama, Kotaro, Yamashita, Atsushi, Yokoyama, Kazuaki, Luo, Yuqian, Kawashima, Akira, Maeda, Yumi, Nakamura, Yasuhiro, Harada, Ayako, Kiriya, Mitsuo, Karasawa, Ken, Suzuki, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997041/
https://ncbi.nlm.nih.gov/pubmed/33770127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249184
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