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A transcription-centric model of SNP-age interaction

Complex age-associated phenotypes are caused, in part, by an interaction between an individual’s genotype and age. The mechanisms governing such interactions are however not entirely understood. Here, we provide a novel transcriptional mechanism-based framework–SNiPage, to investigate such interacti...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Wang, Kun, Basu, Mahashweta, Malin, Justin, Hannenhalli, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997000/
https://ncbi.nlm.nih.gov/pubmed/33770080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009427
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