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Comprehensive map of age-associated splicing changes across human tissues and their contributions to age-associated diseases
Alternative splicing contributes to phenotypic diversity at multiple biological scales, and its dysregulation is implicated in both ageing and age-associated diseases in human. Cross-tissue variability in splicing further complicates its links to age-associated phenotypes and elucidating these links...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053367/ https://ncbi.nlm.nih.gov/pubmed/30026530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29086-2 |
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