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Prevalent Pathogenic Variants of ATP7B in Chinese Patients with Wilson’s Disease: Geographical Distribution and Founder Effect

Wilson’s disease (WD) is an autosomal recessive disorder caused by ATP7B pathogenic variants. This study aimed to show the geographical distribution and haplotype spectrum of three prevalent pathogenic variants (p.R778L, p.P992L, p.T935M) in mainland Chinese population and clarify whether the founde...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Yang, Guo-Min, Wang, Rou-Min, Xia, Nan, Zheng, Zi-Wei, Dong, Yi, Wu, Zhi-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996491/
https://ncbi.nlm.nih.gov/pubmed/33668890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12030336
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