Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

BACKGROUND: To assess the performance of plasma neurofilament light (NfL) and phosphorylated tau 181 (p-tau181) to inform about cerebral Alzheimer’s disease (AD) pathology and predict clinical progression in a memory clinic setting. METHODS: Plasma NfL and p-tau181, along with established cerebrospi...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Clark, Christopher, Lewczuk, Piotr, Kornhuber, Johannes, Richiardi, Jonas, Maréchal, Bénédicte, Karikari, Thomas K., Blennow, Kaj, Zetterberg, Henrik, Popp, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995778/
https://ncbi.nlm.nih.gov/pubmed/33766131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00805-8
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