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β-Hemoglobinopathies lead the way
In this issue of Blood, guided by clinical observations and needs, Gong et al have identified a germline missense mutation in DNA methyltransferase 1 (DNMT1), a ubiquitously expressed key epigenetic regulator, as a cause of hereditary persistence of fetal hemoglobin (HPFH). HPFH protects against β-t...
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| Publicado en: | Blood |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995288/ https://ncbi.nlm.nih.gov/pubmed/33764430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009961 |
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