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Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nano‐delivery system for therapeutic nucleic acids. The great effort put in the development of ionizable lipids with increased in vivo potency brought LNPs from the laboratory benches to the FDA approval of patisiran in 2018 and t...
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| Publicado no: | Bioeng Transl Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995196/ https://ncbi.nlm.nih.gov/pubmed/33786376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10213 |
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