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The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development
Pluripotent cells of the mammalian embryo undergo extensive chromatin rewiring to prepare for lineage commitment after implantation. Repressive H3K27me3, deposited by Polycomb Repressive Complex 2 (PRC2), is reallocated from large blankets in pre-implantation embryos to mark promoters of development...
Guardat en:
| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7994559/ https://ncbi.nlm.nih.gov/pubmed/33767158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21910-0 |
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