Epigenetic Silencing of DAPK1and p16(INK4a) Genes by CpG Island Hypermethylation in Epithelial Ovarian Cancer Patients

Transcriptional silencing induced by hypermethylation of CpG islands in the promoter regions of genes is believed to be an important mechanism of carcinogenesis in human cancers including epithelial ovarian cancer (EOC). Previously published data on gene methylation of EOC focused mainly on single g...

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Veröffentlicht in:Indian J Clin Biochem
Hauptverfasser: Zuberi, Mariyam, Dholariya, Sagar, Khan, Imran, Mir, Rashid, Guru, Sameer, bhat, Musadiq, Sumi, Mamta, Saxena, Alpana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer India 2020
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Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994475/
https://ncbi.nlm.nih.gov/pubmed/33867711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12291-020-00888-4
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