Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence

Coagulase-negative staphylococci and Staphylococcus aureus colonize similar niches in mammals and conceivably compete for space and nutrients. Here, we report that a coagulase-negative staphylococcus, Staphylococcus chromogenes ATCC43764, synthesizes and secretes 6-thioguanine (6-TG), a purine analo...

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Udgivet i:Nat Commun
Main Authors: Chin, Denny, Goncheva, Mariya I., Flannagan, Ronald S., Deecker, Shayna R., Guariglia-Oropeza, Veronica, Ensminger, Alexander W., Heinrichs, David E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994395/
https://ncbi.nlm.nih.gov/pubmed/33767207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22175-3
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