Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds

Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases, thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) which are bacterial virulence factors, and the human matrix metalloproteases MMP-9 and −14. Inhibition of virulence is a putative strategy i...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Rahman, Fatema, Nguyen, Tra-Mi, Adekoya, Olayiwola A, Campestre, Cristina, Tortorella, Paolo, Sylte, Ingebrigt, Winberg, Jan-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993378/
https://ncbi.nlm.nih.gov/pubmed/33757387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1901088
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